Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a competitive agonist for the CB1/CB2 receptors. It exhibits CB1/CB2 agonistic activity by binding to the human CB1 and CB2 receptors, with Ki values of 5.9 nM and 3.5 nM, respectively [1].
Pack Size | Availability | Price/USD | Quantity |
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2 mg | 5 days | $ 58.00 |
Description | CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a competitive agonist for the CB1/CB2 receptors. It exhibits CB1/CB2 agonistic activity by binding to the human CB1 and CB2 receptors, with Ki values of 5.9 nM and 3.5 nM, respectively [1]. |
In vitro | CB1/2 agonist 3 (compound 52) exhibits a partial agonistic activity by inducing [35 S]GTPγS binding to hCB1-CHO cell membranes with an EC50 of 30.99 nM, and demonstrates a slight inhibitory effect on [35 S]GTPγS binding to hCB2-CHO cell membranes, with an EC50 of 1.28 nM [1]. Additionally, at a concentration of 1 μM for 1 hour, it acts as an antagonist to the CB1/CB2 agonist CP-55940, showing a K b value of 78.17 nM [1]. |
Molecular Weight | 387.6 |
Formula | C25H41NO2 |
CAS No. | 2772655-86-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CB1/2 agonist 3 2772655-86-2 inhibitor inhibit