Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.
Atigotatug (FUT8-KO)
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Catalog No. T9901A-1662
Alias BMS-986012 (FUT8-KO)
Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.
Atigotatug (FUT8-KO)
Cas No. 2733581-82-1
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Quantity
1 mg
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5 mg
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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.
Synonyms
BMS-986012 (FUT8-KO)
Chemical Properties
Cas No.
2733581-82-1
Storage & Solubility Information
Storage
store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
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