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Atigotatug (FUT8-KO)

😃Good
Catalog No. T9901A-1662Cas No. 2733581-82-1
Alias BMS-986012 (FUT8-KO)

Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.

Atigotatug (FUT8-KO)

Atigotatug (FUT8-KO)

😃Good
Catalog No. T9901A-1662Alias BMS-986012 (FUT8-KO)Cas No. 2733581-82-1
Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.
SynonymsBMS-986012 (FUT8-KO)
Chemical Properties
Cas No.2733581-82-1
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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