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Aletekitug
(Synonyms: GSK1070806, GSK 1070806) Copy Product Info
🥰Excellent
Synonyms: GSK1070806, GSK 1070806
Catalog No. T77429 Copy Product Info
🥰Excellent
Aletekitug is a humanized antibody that targets IL-18. Alekitug binds to free IL-18, thereby blocking its interaction with the IL-18 receptor α/β heterodimer and preventing receptor activation. This inhibits the release of pro-inflammatory cytokines, reduces the infiltration of immune cells at sites of inflammation, and exerts an anti-inflammatory effect. Alekitug can be used in research on inflammatory conditions such as inflammatory bowel disease.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $447 | - | In Stock | |
| 5 mg | $1,400 | - | In Stock | |
| 10 mg | $2,240 | - | In Stock | |
| 25 mg | $4,210 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95.0% (SDS-PAGE); >95.0% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
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| Description | Aletekitug is a humanized antibody that targets IL-18. Alekitug binds to free IL-18, thereby blocking its interaction with the IL-18 receptor α/β heterodimer and preventing receptor activation. This inhibits the release of pro-inflammatory cytokines, reduces the infiltration of immune cells at sites of inflammation, and exerts an anti-inflammatory effect. Alekitug can be used in research on inflammatory conditions such as inflammatory bowel disease. |
| Targets & IC50 | IL-18:10.16 ng/mL (EC50) |
| Synonyms | GSK1070806, GSK 1070806 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-18 Protein (His) at 2 μg/mL (30 μL/well) can bind Aletekitug. The EC50 is 226.2 ng/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-18 |
| Molecular Weight | 147.38 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Aletekitug chemical structure | Aletekitug molecular weight
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