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5-Nonadecylresorcinol is a natural alkylresorcinol isolated from wheat bran. This product exhibits significant anti-degranulation activity in the RBL-2H3 cell model, effectively inhibiting DNP-BSA-induced release of β-hexosaminidase. It shows no cytotoxicity at experimental concentrations and serves as a pharmacological tool for researching natural anti-allergic agents and their mechanisms in mast-cell-like cells.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $29 | - | In Stock |
| Description | 5-Nonadecylresorcinol is a natural alkylresorcinol isolated from wheat bran. This product exhibits significant anti-degranulation activity in the RBL-2H3 cell model, effectively inhibiting DNP-BSA-induced release of β-hexosaminidase. It shows no cytotoxicity at experimental concentrations and serves as a pharmacological tool for researching natural anti-allergic agents and their mechanisms in mast-cell-like cells. |
| In vitro | In cell-based assays, 5-Nonadecylresorcinol demonstrates dose-dependent inhibition of antigen-stimulated degranulation in RBL-2H3 cells; the compound significantly reduces the secretion of β-hexosaminidase, a key marker of allergic response, while maintaining high cell viability as measured by MTT assays [1]. |
| Molecular Weight | 376.62 |
| Formula | C25H44O2 |
| Cas No. | 35176-46-6 |
| Smiles | OC=1C=C(O)C=C(C1)CCCCCCCCCCCCCCCCCCC |
| Relative Density. | 0.942g/cm3 |
| Storage | store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (212.42 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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