Shopping Cart

Your shopping cart is currently empty

MT-4

Name: MT-4
Brand: TargetMol
SKU: T13783
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T13783Cas No. 2327925-35-7

MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.

MT-4

😃Good

Purity: 99.69%

Catalog No. T13783Cas No. 2327925-35-7

MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$36	In Stock	In Stock
5 mg	$62	In Stock	In Stock
10 mg	$100	In Stock	In Stock
25 mg	$167	In Stock	In Stock
50 mg	$238	In Stock	In Stock
100 mg	$323	In Stock	In Stock
200 mg	$446	-	In Stock
1 mL x 10 mM (in DMSO)	$68	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.69%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.
In vitro	In an in vivo model measuring intraperitoneal dissemination, MT4 and MT6 inhibited the adhesion of ovarian cancer cells to the peritoneum. Pretreatment with MT4 also sensitized ovarian cancer cells to paclitaxel. The data support continued optimization of the new class of SMIs that block the TG2/FN complex at the interface between cancer cells and the tumor niche[1].

Chemical Properties

Molecular Weight	361.44
Formula	C₂₁H₂₃N₅O
Cas No.	2327925-35-7
Smiles	CN(C)c1cc(C)nc(Nc2ccc(NC(=O)Cc3ccccc3)cc2)n1
Relative Density.	1.246 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (249 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7667 mL	13.8336 mL	27.6671 mL	138.3355 mL
5 mM	0.5533 mL	2.7667 mL	5.5334 mL	27.6671 mL
10 mM	0.2767 mL	1.3834 mL	2.7667 mL	13.8336 mL
20 mM	0.1383 mL	0.6917 mL	1.3834 mL	6.9168 mL
50 mM	0.0553 mL	0.2767 mL	0.5533 mL	2.7667 mL
100 mM	0.0277 mL	0.1383 mL	0.2767 mL	1.3834 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc