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ALC-0315

Name: ALC-0315
Brand: TargetMol
SKU: T9277
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9277Cas No. 2036272-55-4

ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine

ALC-0315

🥰Excellent

Purity: 99.66%

Catalog No. T9277Cas No. 2036272-55-4

ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$57	In Stock
10 mg	$78	In Stock
25 mg	$121	In Stock
50 mg	$173	In Stock
100 mg	$255	In Stock
200 mg	$377	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.66%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine

Chemical Properties

Molecular Weight	766.27
Formula	C₄₈H₉₅NO₅
Cas No.	2036272-55-4
Smiles	CCCCCCCCC(CCCCCC)C(=O)OCCCCCCN(CCCCO)CCCCCCOC(=O)C(CCCCCC)CCCCCCCC
Relative Density.	0.919 g/cm3 (Predicted)
Color	Transparent
Appearance	Viscous

Storage & Solubility Information

Storage

keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (130.5 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (5.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3050 mL	6.5251 mL	13.0502 mL	65.2512 mL
5 mM	0.2610 mL	1.3050 mL	2.6100 mL	13.0502 mL
10 mM	0.1305 mL	0.6525 mL	1.3050 mL	6.5251 mL
20 mM	0.0653 mL	0.3263 mL	0.6525 mL	3.2626 mL
50 mM	0.0261 mL	0.1305 mL	0.2610 mL	1.3050 mL
100 mM	0.0131 mL	0.0653 mL	0.1305 mL	0.6525 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc