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Ginsenoside F4

🥰Excellent
Catalog No. TN1093Cas No. 181225-33-2

Ginsenoside F4 exerts inhibitory effects on human lymphocytoma JK cells by inducing apoptosis. The mechanism of action involves mitochondrial dysfunction, increased Bax expression, and reduced Bcl-2 expression, together resulting in programmed cell death.

Ginsenoside F4

Ginsenoside F4

🥰Excellent
Purity: 97.336%
Catalog No. TN1093Cas No. 181225-33-2
Ginsenoside F4 exerts inhibitory effects on human lymphocytoma JK cells by inducing apoptosis. The mechanism of action involves mitochondrial dysfunction, increased Bax expression, and reduced Bcl-2 expression, together resulting in programmed cell death.
Pack SizePriceAvailabilityQuantity
1 mg$81In Stock
5 mg$228In Stock
10 mg$342In Stock
25 mg$572In Stock
50 mg$813In Stock
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Purity:97.336%
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Product Introduction

Bioactivity
Description
Ginsenoside F4 exerts inhibitory effects on human lymphocytoma JK cells by inducing apoptosis. The mechanism of action involves mitochondrial dysfunction, increased Bax expression, and reduced Bcl-2 expression, together resulting in programmed cell death.
In vitro
Methods: Ginsenoside F4 (8.15 μM, 65.19 μM, 130.38 μM) was used to treat Homo sapiens lymphoblastoma JK cells, and the expression of related proteins was detected by Western Blot.
Results: Ginsenoside F4 induced apoptosis in Homo sapiens lymphoblastoma JK cells by downregulating Bcl-2 protein and upregulating Bax protein levels, which are key regulators associated with apoptosis, demonstrating its antitumor effects. [1]
Chemical Properties
Molecular Weight767.01
FormulaC42H70O12
Cas No.181225-33-2
SmilesC[C@]12[C@@]3(C)[C@@]([C@@H](\C(=C\CC=C(C)C)\C)CC3)([C@H](O)C[C@@]1([C@]4(C)[C@@]([C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)C2)(C(C)(C)[C@@H](O)CC4)[H])[H])[H]
Relative Density.1.28 g/cm3 at 20℃
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (52.15 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3038 mL6.5188 mL13.0376 mL65.1882 mL
5 mM0.2608 mL1.3038 mL2.6075 mL13.0376 mL
10 mM0.1304 mL0.6519 mL1.3038 mL6.5188 mL
20 mM0.0652 mL0.3259 mL0.6519 mL3.2594 mL
50 mM0.0261 mL0.1304 mL0.2608 mL1.3038 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

Ginsenoside F-4
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