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DEAE-dextran, MW 500000 hydrochloride
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Catalog No. TSW-00892Cas No. 9064-91-9
Alias Diethylaminoethyl-dextran, MW 500000 hydrochloride, DEAE-dextran, MW 500000 (hydrochloride), from bacterial (Leuconostoc mesenteroides), DEAE-dextran (MW 500000 hydrochloride)
DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial [Leuconostoc mesenteroides]) is a high molecular weight, positively charged polymer that notably enhances the uptake of viral RNA by cultured cells. It is employed in "tumor immunity" RNA-spleen cell transfer systems, significantly prolonging the lifespan of tumor-bearing animals, comparable to those with active immunity. DEAE-dextran acts as a nucleic acid complexing agent, forming composite particles with DNA/RNA, and is widely used in gene delivery. Additionally, it serves as a coating for liposomes.
DEAE-dextran, MW 500000 hydrochloride
DEAE-dextran, MW 500000 hydrochloride
Copy Product Info😃Good
Catalog No. TSW-00892Alias Diethylaminoethyl-dextran, MW 500000 hydrochloride, DEAE-dextran, MW 500000 (hydrochloride), from bacterial (Leuconostoc mesenteroides), DEAE-dextran (MW 500000 hydrochloride)Cas No. 9064-91-9
DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial [Leuconostoc mesenteroides]) is a high molecular weight, positively charged polymer that notably enhances the uptake of viral RNA by cultured cells. It is employed in "tumor immunity" RNA-spleen cell transfer systems, significantly prolonging the lifespan of tumor-bearing animals, comparable to those with active immunity. DEAE-dextran acts as a nucleic acid complexing agent, forming composite particles with DNA/RNA, and is widely used in gene delivery. Additionally, it serves as a coating for liposomes.
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| Description | DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial [Leuconostoc mesenteroides]) is a high molecular weight, positively charged polymer that notably enhances the uptake of viral RNA by cultured cells. It is employed in "tumor immunity" RNA-spleen cell transfer systems, significantly prolonging the lifespan of tumor-bearing animals, comparable to those with active immunity. DEAE-dextran acts as a nucleic acid complexing agent, forming composite particles with DNA/RNA, and is widely used in gene delivery. Additionally, it serves as a coating for liposomes. |
| Synonyms | Diethylaminoethyl-dextran, MW 500000 hydrochloride, DEAE-dextran, MW 500000 (hydrochloride), from bacterial (Leuconostoc mesenteroides), DEAE-dextran (MW 500000 hydrochloride) |
| Molecular Weight | 500000 (Average) |
| Cas No. | 9064-91-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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