Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 35 days | $ 660.00 | |
50 mg | 35 days | $ 2,760.00 |
Description | JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells. |
Targets&IC50 | CX3CR1:0.32 nM (IC50) |
In vivo | JMS-17-2 (10 mg/kg; administered i.p.; twice a day for three weeks) significantly reduces tumor presence in the skeletal and visceral organs of SCID mice with MDA-231 xenografts[1]. The consistent dosage regimen and application method underscore its effectiveness in this specific animal model, demonstrating a promising avenue for further research into its anti-tumor capabilities. |
Molecular Weight | 456.41 |
Formula | C25H27Cl2N3O |
CAS No. | 2341841-07-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JMS-17-2 hydrochloride 2341841-07-2 JMS 17 2 hydrochloride JMS-17-2 Hydrochloride JMS172 hydrochloride inhibitor inhibit