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Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $490 | In Stock | In Stock | |
| 5 mg | $1,130 | In Stock | In Stock | |
| 10 mg | $1,520 | In Stock | In Stock | |
| 25 mg | $2,250 | In Stock | In Stock | |
| 50 mg | $2,970 | In Stock | In Stock |
| Description | Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway. |
| In vitro | Fusarochromanone (10 μM; 24 hours) treatment of HaCaT and P9-WT cell lines resulted in cells being in the G2 and M phases of the cell cycle for both cell lines[1]. |
| In vivo | Fusarochromanone (8 mg/kg; administered intraperitoneally 5 days per week for 3.5 weeks) treatment of SCID Beige mice inoculated with SRB12-p9 cells resulted in a 30% reduction in tumor volume. |
| Synonyms | NSC-627608, NSC 627608, FC-101, FC101, FC 101 |
| Molecular Weight | 292.33 |
| Formula | C15H20N2O4 |
| Cas No. | 802915-53-3 |
| Smiles | NC1=C2C(=CC=C1C(C[C@H](CO)N)=O)OC(C)(C)CC2=O |
| Relative Density. | 1.267 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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