Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

MAIT-203 acetate

😃Good
Catalog No. TP3070

MAIT-203 acetate is a cyclopentylglycine-derived peptidomimetic that effectively inhibits the interaction between adenomatous polyposis coli (APC) and Asef (RhoGEF4), while not affecting the APC-Sam68 or APC-striatin interactions. It binds to APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM, significantly impeding the migration and invasion of colorectal cancer cells.

MAIT-203 acetate

MAIT-203 acetate

😃Good
Catalog No. TP3070
MAIT-203 acetate is a cyclopentylglycine-derived peptidomimetic that effectively inhibits the interaction between adenomatous polyposis coli (APC) and Asef (RhoGEF4), while not affecting the APC-Sam68 or APC-striatin interactions. It binds to APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM, significantly impeding the migration and invasion of colorectal cancer cells.
Pack SizePriceAvailabilityQuantity
1 mg$98 7-10 days
5 mgPreferential7-10 days
Add to Cart
Add to Quotation
Bulk & Custom
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
MAIT-203 acetate is a cyclopentylglycine-derived peptidomimetic that effectively inhibits the interaction between adenomatous polyposis coli (APC) and Asef (RhoGEF4), while not affecting the APC-Sam68 or APC-striatin interactions. It binds to APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM, significantly impeding the migration and invasion of colorectal cancer cells.
In vitro
MAIT-203 (10 μM and 25 μM; for 24 h) acetate reduces the interaction between Asef and APC in a dose-dependent manner in HEK293T cells [1]. Additionally, MAIT-203 (10 μM) acetate significantly reduces the migration of SW480 and HCT116 cells [1]. Incubating SW480 cells with MAIT-203 (25, 50 μM; 24 hours) acetate leads to a dose-dependent decrease in the active form of CDC42, while Rac1 remains unaffected [1].
Chemical Properties
Molecular Weight2517.85 (free base)
FormulaC108H121N43O31
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy MAIT-203 acetate | purchase MAIT-203 acetate | MAIT-203 acetate cost | order MAIT-203 acetate | MAIT-203 acetate in vitro | MAIT-203 acetate formula | MAIT-203 acetate molecular weight