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Peplomycin (Bleomycin PEP) sulfate is an analog of Bleomycin and functions as an antitumor antibiotic. It exhibits strong antitumor activity with reduced pulmonary toxicity. Peplomycin sulfate can induce various skin abnormalities and apoptosis in oral squamous carcinoma SSCKN cells. Additionally, it is used to induce pulmonary fibrosis. Peplomycin sulfate is applicable in research related to tumors, pulmonary fibrosis, and other diseases.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Peplomycin (Bleomycin PEP) sulfate is an analog of Bleomycin and functions as an antitumor antibiotic. It exhibits strong antitumor activity with reduced pulmonary toxicity. Peplomycin sulfate can induce various skin abnormalities and apoptosis in oral squamous carcinoma SSCKN cells. Additionally, it is used to induce pulmonary fibrosis. Peplomycin sulfate is applicable in research related to tumors, pulmonary fibrosis, and other diseases. |
| Synonyms | Pepleomycin sulfate, Bleomycin PEP sulfate |
| Molecular Weight | 1571.67 |
| Formula | C61H90N18O25S3 |
| Cas No. | 70384-29-1 |
| Smiles | S(=O)(=O)(O)O.[C@H]([C@H](NC(=O)C1=NC([C@@H](NC[C@@H](C(N)=O)N)CC(N)=O)=NC(N)=C1C)C(N[C@@H]([C@H]([C@@H](C(N[C@H](C(NCCC2=NC(=CS2)C3=NC(C(NCCCN[C@@H](C)C4=CC=CC=C4)=O)=CS3)=O)[C@@H](C)O)=O)C)O)C)=O)(O[C@H]5[C@@H](O[C@@H]6[C@@H](O)[C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O6)[C@@H](O)[C@H](O)[C@H](CO)O5)C7=CN=CN7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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