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5-A-RU hydrochloride

Name: 5-A-RU hydrochloride
Brand: TargetMol
SKU: T10165L
Price: 1520 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: 5-Amino-6-(D-ribitylamino)uracil hydrochloride) Copy Product Info

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Synonyms: 5-Amino-6-(D-ribitylamino)uracil hydrochloride

Catalog No. T10165L Copy Product Info

Purity: 98.27%

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5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is a metabolic intermediate, a MAIT cell activator that activates mucosal-associated invariant T cells, and is used for research on breast cancer and prostate cancer.

Cas No. 134452-11-2

Pack Size	Price	USA Stock	Global Stock
1 mg	$195	In Stock	In Stock
5 mg	$485	In Stock	In Stock
10 mg	$693	In Stock	In Stock
25 mg	$1,070	In Stock	-
50 mg	$1,520	-	In Stock
100 mg	Inquiry	2-4 weeks	2-4 weeks

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.27%

Appearance:Solid

Color:Pink to Black

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COA HPLC HNMR IC

Product Introduction

Bioactivity

Description	5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is a metabolic intermediate, a MAIT cell activator that activates mucosal-associated invariant T cells, and is used for research on breast cancer and prostate cancer.
In vitro	Methods: Human MAIT cells were stimulated with 5-A-RU hydrochloride (2 μM), and human and mouse MR1 tetramers were produced for MAIT cell identification. Results: 5-A-RU hydrochloride effectively stimulated human MAIT cells and was successfully used for the production of human and mouse MR1 tetramers. [1]
In vivo	Methods: 5-A-RU hydrochloride (100 nM) was mixed with MeG in vitro, then administered to iVα19 Cα−/−-Tg mice via intraperitoneal injection (i.p.) for 18 hours. Results: This treatment activated MAIT cells in mice. [2]
Synonyms	5-Amino-6-(D-ribitylamino)uracil hydrochloride

Chemical Properties

Molecular Weight	312.71
Formula	C₉H₁₇ClN₄O₆
Cas No.	134452-11-2
Smiles	N(C[C@@H]([C@@H]([C@@H](CO)O)O)O)C1=C(N)C(=O)NC(=O)N1.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Store at low temperature,Store under nitrogen,Keep away from moisture,Keep away from direct sunlight Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (319.79 mM), Sonication and heating are recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.1979 mL	15.9893 mL	31.9785 mL	159.8926 mL
5 mM	0.6396 mL	3.1979 mL	6.3957 mL	31.9785 mL
10 mM	0.3198 mL	1.5989 mL	3.1979 mL	15.9893 mL
20 mM	0.1599 mL	0.7995 mL	1.5989 mL	7.9946 mL
50 mM	0.0640 mL	0.3198 mL	0.6396 mL	3.1979 mL
100 mM	0.0320 mL	0.1599 mL	0.3198 mL	1.5989 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

5-A-RU Hydrochloride5ARU hydrochloride5 A RU hydrochloride

Related Tags: 5-A-RU hydrochloride chemical structure | 5-A-RU hydrochloride in vivo | 5-A-RU hydrochloride in vitro | 5-A-RU hydrochloride formula | 5-A-RU hydrochloride molecular weight