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5-A-RU hydrochloride

Name: 5-A-RU hydrochloride
Brand: TargetMol
SKU: T10165L
Price: 1520 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10165LCas No. 134452-11-2

Alias 5-Amino-6-(D-ribitylamino)uracil hydrochloride

5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prostate cancer.

5-A-RU hydrochloride

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Purity: 98.27%

Catalog No. T10165LAlias 5-Amino-6-(D-ribitylamino)uracil hydrochlorideCas No. 134452-11-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
5 mg	$485	In Stock	In Stock
10 mg	$693	In Stock	In Stock
25 mg	$1,070	In Stock	In Stock
50 mg	$1,520	-	In Stock
100 mg	Inquiry	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.27%

Appearance:Solid

Color:Pink to Black

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COA IC HPLC HNMR

Product Introduction

Bioactivity

Description	5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prostate cancer.
In vitro	5-A-RU hydrochloride (2 μM) can be used to stimulate human MAIT cells and produce MR1 tetramers for identification of human and mouse MAIT cells[1].
In vivo	When 5-A-RU hydrochloride (100 nM; i.p.; 18 hours) and MeG were mixed ex tempore prior to in vivo injection, MAIT cells in iVα19 Cα−/−-Tg mice were activated[2].
Synonyms	5-Amino-6-(D-ribitylamino)uracil hydrochloride

Chemical Properties

Molecular Weight	312.71
Formula	C₉H₁₇ClN₄O₆
Cas No.	134452-11-2
Smiles	N(C[C@@H]([C@@H]([C@@H](CO)O)O)O)C1=C(N)C(=O)NC(=O)N1.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature,store under nitrogen,keep away from moisture,keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (319.79 mM), Sonication and heating are recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.1979 mL	15.9893 mL	31.9785 mL	159.8926 mL
5 mM	0.6396 mL	3.1979 mL	6.3957 mL	31.9785 mL
10 mM	0.3198 mL	1.5989 mL	3.1979 mL	15.9893 mL
20 mM	0.1599 mL	0.7995 mL	1.5989 mL	7.9946 mL
50 mM	0.0640 mL	0.3198 mL	0.6396 mL	3.1979 mL
100 mM	0.0320 mL	0.1599 mL	0.3198 mL	1.5989 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5-A-RU Hydrochloride5ARU hydrochloride5 A RU hydrochloride