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Fulvic Acid

Catalog No. T38108   CAS 479-66-3

Fulvic Acid is a natural product of humus produced by microorganisms in soil, sediment or aquatic environments. Fulvic acid is a phenolic acid and fungal metabolite isolated from Penicillium for the first time. Fulvic Acid inhibits the dimerization of amyloid b (17-42) (AB17-42), destroys the pre-formed trimer of AB17-42, and binds to the catalytic site of phosphodiesterase 5A (PDE5A), which can regulate the body's immune system, affect the oxidation state of cells, and improve gastrointestinal function. Fulvic Acid can be used as an oxidant or reducing agent and has the potential to study chronic inflammatory diseases such as diabetes.

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Fulvic Acid Chemical Structure
Fulvic Acid, CAS 479-66-3
Pack Size Availability Price/USD Quantity
1 mg 5 days $ 88.00
5 mg 5 days $ 132.00
1 mL * 10 mM (in DMSO) 5 days $ 172.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Fulvic Acid is a natural product of humus produced by microorganisms in soil, sediment or aquatic environments. Fulvic acid is a phenolic acid and fungal metabolite isolated from Penicillium for the first time. Fulvic Acid inhibits the dimerization of amyloid b (17-42) (AB17-42), destroys the pre-formed trimer of AB17-42, and binds to the catalytic site of phosphodiesterase 5A (PDE5A), which can regulate the body's immune system, affect the oxidation state of cells, and improve gastrointestinal function. Fulvic Acid can be used as an oxidant or reducing agent and has the potential to study chronic inflammatory diseases such as diabetes.
In vitro Fulvic acid (15 mg/L) enhanced growth and achieved the highest EPA content (13.9%) in the evolved diatom. Fulvic acid enhanced antioxidant potential and unprecedently governed the expression of PUFA and lipid biosynthetic genes. This investigation demonstrates the efficacy of adaptive evolution empowered by fulvic acid.[1] Embryogenic cell masses (ECM) of Abies cephalonica were grown on proliferation media in the presence and absence of fulvic acid (FA), FA increased the proliferation rate, especially during the early sampling days, and the percentage of PEM in their advanced developmental stage. During the maturation phase, fulvic matter also induced a delay in somatic embryo formation. The structure-activity relationship observed here suggests that the influence of FA on ECM may be attributed to specific bioactive molecules that are preferentially released from the FA loose superstructure.[2]
Molecular Weight 308.24
Formula C14H12O8
CAS No. 479-66-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.08 mg/mL (10 mM), Sonication is recommended.

Methanol: Soluble

Chloroform: Soluble

TargetMolReferences and Literature

1. Wang X, et al. Adaptive evolution of microalgal strains empowered by fulvic acid for enhanced polyunsaturated fatty acid production. Bioresour Technol. 2019;277:204-210. 2. Zancani M, et al. Fulvic acid affects proliferation and maturation phases in Abies cephalonica embryogenic cells. J Plant Physiol. 2011;168(11):1226-1233.

Related compound libraries

This product is contained In the following compound libraries:
Microbial Natural Product Library

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Keywords

Fulvic Acid 479-66-3 Metabolism oxidation-reduction PDE Antioxidant inhibitor inhibit

 

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