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Anti-Mouse 4-1BB/CD137 Antibody (3H3) (Synonyms: 3H3)
Catalog No. T9901A-632 Copy Product Info
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Anti-Mouse 4-1BB/CD137 Antibody (3H3) is a monoclonal inhibitory antibody targeting mouse 4-1BB/CD137. It can effectively activate memory T cells and exert anti-tumor effects by upregulating the expression levels of Bcl-xL and granzyme B, and is applicable to research on various tumors such as lymphoma and colon cancer.
Anti-Mouse 4-1BB/CD137 Antibody (3H3)
Copy Product Info🥰Excellent
Catalog No. T9901A-632
Synonyms 3H3
Anti-Mouse 4-1BB/CD137 Antibody (3H3) is a monoclonal inhibitory antibody targeting mouse 4-1BB/CD137. It can effectively activate memory T cells and exert anti-tumor effects by upregulating the expression levels of Bcl-xL and granzyme B, and is applicable to research on various tumors such as lymphoma and colon cancer.
Anti-Mouse 4-1BB/CD137 Antibody
(3H3)
(3H3)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $98 | Inquiry | Inquiry | |
| 5 mg | $355 | Inquiry | Inquiry | |
| 10 mg | Preferential | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Mouse 4-1BB/CD137 Antibody (3H3) is a monoclonal inhibitory antibody targeting mouse 4-1BB/CD137. It can effectively activate memory T cells and exert anti-tumor effects by upregulating the expression levels of Bcl-xL and granzyme B, and is applicable to research on various tumors such as lymphoma and colon cancer. |
| In vitro | Anti-Mouse 4-1BB/CD137 Antibody (3H3) at 10 μg/mL significantly upregulates the expression levels of Bcl-xL and granzyme B in memory T cells derived from OT-I mice after 2 days of treatment [1]. |
| In vivo | In wild‑type C57BL/6 mice bearing E.G7 tumors, intraperitoneal injection of 100 μg Anti-Mouse 4-1BB/CD137 Antibody (3H3) on days 8 and 11 shows significant antitumor activity [1]. In female BALB/c mice bearing CT26hEGFR tumors, intraperitoneal injection of Anti-Mouse 4-1BB/CD137 Antibody (3H3) at 4 mg/kg every 2 days for a total of 3 doses markedly inhibits tumor growth [2]. |
| Synonyms | 3H3 |
| Clone | 3H3 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | 4-1BB/CD137 |
| Molecular Weight | 150 kDa |
| Storage | Store at -20°C Shipping with blue ice. |
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