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Anti-Mouse 4-1BB/CD137 Antibody (3H3)

(Synonyms: 3H3) Copy Product Info
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Synonyms: 3H3

Catalog No. T9901A-632 Copy Product Info
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Anti-Mouse 4-1BB/CD137 Antibody (3H3) is a monoclonal inhibitory antibody targeting mouse 4-1BB/CD137. It can effectively activate memory T cells and exert anti-tumor effects by upregulating the expression levels of Bcl-xL and granzyme B, and is applicable to research on various tumors such as lymphoma and colon cancer.

Anti-Mouse 4-1BB/CD137 Antibody
(3H3)

Pack SizePriceUSA StockGlobal StockQuantity
1 mg$98InquiryInquiry
5 mg$355InquiryInquiry
10 mgPreferentialInquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Mouse 4-1BB/CD137 Antibody (3H3) is a monoclonal inhibitory antibody targeting mouse 4-1BB/CD137. It can effectively activate memory T cells and exert anti-tumor effects by upregulating the expression levels of Bcl-xL and granzyme B, and is applicable to research on various tumors such as lymphoma and colon cancer.
In vitro
Anti-Mouse 4-1BB/CD137 Antibody (3H3) at 10 μg/mL significantly upregulates the expression levels of Bcl-xL and granzyme B in memory T cells derived from OT-I mice after 2 days of treatment [1].
In vivo
In wild‑type C57BL/6 mice bearing E.G7 tumors, intraperitoneal injection of 100 μg Anti-Mouse 4-1BB/CD137 Antibody (3H3) on days 8 and 11 shows significant antitumor activity [1].
In female BALB/c mice bearing CT26hEGFR tumors, intraperitoneal injection of Anti-Mouse 4-1BB/CD137 Antibody (3H3) at 4 mg/kg every 2 days for a total of 3 doses markedly inhibits tumor growth [2].
Synonyms3H3
Clone
3H3
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
Target4-1BB/CD137
Chemical Properties
Molecular Weight150 kDa
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-Mouse 4-1BB/CD137 Antibody (3H3) in vivo | Anti-Mouse 4-1BB/CD137 Antibody (3H3) in vitro | Anti-Mouse 4-1BB/CD137 Antibody (3H3) molecular weight