HDAC6-IN-31

Name: HDAC6-IN-31
Brand: TargetMol
SKU: T209038
Rating: 4.5 (1 reviews)

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Catalog No. T209038

HDAC6-IN-31 (compound 8m) is a selective HDAC6 inhibitor with an IC50 of 0.026 μM. It significantly suppresses the production and release of pro-inflammatory cytokines. HDAC6 plays a crucial role in inhibiting inflammasome activation and holds potential for treating NLRP3 inflammasome-driven inflammatory diseases. Additionally, HDAC6-IN-31 inhibits the migration of glioblastoma cells.

HDAC6-IN-31

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Catalog No. T209038

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	HDAC6-IN-31 (compound 8m) is a selective HDAC6 inhibitor with an IC50 of 0.026 μM. It significantly suppresses the production and release of pro-inflammatory cytokines. HDAC6 plays a crucial role in inhibiting inflammasome activation and holds potential for treating NLRP3 inflammasome-driven inflammatory diseases. Additionally, HDAC6-IN-31 inhibits the migration of glioblastoma cells.
Targets&IC50	HDAC6:0.026 μM, HDAC1:3.07 μM

Chemical Properties

Formula

C₁₅H₁₃FN₄O₂

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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