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TTX-080 is a first-in-class monoclonal antibody targeting human leukocyte antigen G (HLA-G), acting by blocking the binding of HLA-G to its inhibitory receptors such as ILT2 and ILT4. The compound is an essential tool for investigating tumor immune escape mechanisms, aiming to restore the killing efficacy of immune cells against malignant tissues by lifting the HLA-G-mediated checkpoint signaling.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | TTX-080 is a first-in-class monoclonal antibody targeting human leukocyte antigen G (HLA-G), acting by blocking the binding of HLA-G to its inhibitory receptors such as ILT2 and ILT4. The compound is an essential tool for investigating tumor immune escape mechanisms, aiming to restore the killing efficacy of immune cells against malignant tissues by lifting the HLA-G-mediated checkpoint signaling. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | HLA-G |
| Isotype | IgG1-LALA-GA-EM |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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