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FGFR-IN-17

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Catalog No. T206090

FGFR-IN-17 (Compound 12l) is an orally active irreversible inhibitor of FGFR, effectively suppressing both FGFR and its mutants. It inhibits the proliferation and migration of non-small cell lung cancer cells and induces apoptosis. FGFR-IN-17 demonstrates anti-tumor activity.

FGFR-IN-17

FGFR-IN-17

😃Good
Catalog No. T206090
FGFR-IN-17 (Compound 12l) is an orally active irreversible inhibitor of FGFR, effectively suppressing both FGFR and its mutants. It inhibits the proliferation and migration of non-small cell lung cancer cells and induces apoptosis. FGFR-IN-17 demonstrates anti-tumor activity.
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Product Introduction

Bioactivity
Description
FGFR-IN-17 (Compound 12l) is an orally active irreversible inhibitor of FGFR, effectively suppressing both FGFR and its mutants. It inhibits the proliferation and migration of non-small cell lung cancer cells and induces apoptosis. FGFR-IN-17 demonstrates anti-tumor activity.
Targets&IC50
FGFR1:7.24 nM
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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