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Ninerafaxstat trihydrochloride (Synonyms: Ninerafaxstat trihydrochloride(2254741-41-6 Free base))

Name: Ninerafaxstat trihydrochloride
Brand: TargetMol
SKU: T9768L
Price: 67 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T9768L Copy Product Info

Purity: 99.71%

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Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereby inhibiting the proliferation and growth of cancer cells.

Ninerafaxstat trihydrochloride

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Catalog No. T9768L

Synonyms Ninerafaxstat trihydrochloride(2254741-41-6 Free base)

Cas No. 2311824-72-1

Pack Size	Price	USA Stock	Global Stock
1 mg	$67	-	In Stock
5 mg	$162	-	In Stock
10 mg	$238	-	In Stock
25 mg	$397	-	In Stock
50 mg	$575	-	In Stock
100 mg	$786	-	In Stock
1 mL x 10 mM (in DMSO)	$178	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.71%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereby inhibiting the proliferation and growth of cancer cells.
Synonyms	Ninerafaxstat trihydrochloride(2254741-41-6 Free base)

Chemical Properties

Molecular Weight	524.87
Formula	C₂₂H₃₂Cl₃N₃O₅
Cas No.	2311824-72-1
Smiles	Cl.Cl.Cl.COc1ccc(CN2CCN(CCOC(=O)c3cccnc3)CC2)c(OC)c1OC
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 82.92 mg/mL (157.98 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9052 mL	9.5262 mL	19.0523 mL	95.2617 mL
5 mM	0.3810 mL	1.9052 mL	3.8105 mL	19.0523 mL
10 mM	0.1905 mL	0.9526 mL	1.9052 mL	9.5262 mL
20 mM	0.0953 mL	0.4763 mL	0.9526 mL	4.7631 mL
50 mM	0.0381 mL	0.1905 mL	0.3810 mL	1.9052 mL
100 mM	0.0191 mL	0.0953 mL	0.1905 mL	0.9526 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ninerafaxstat TrihydrochlorideNinerafaxstat

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