CYM5442 hydrochloride

Name: CYM5442 hydrochloride
Brand: TargetMol
SKU: T41144
Rating: 4.5 (1 reviews)

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Catalog No. T41144Cas No. 1783987-80-3

Alias CYM 5442 hydrochloride

CYM 5442 hydrochloride is a potent and selective S1P1agonistin vitro(EC50 = 1.35 nM). Activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. Induces acute lymphopenia in mice. Brain penetrant.

CYM5442 hydrochloride

😃Good

Catalog No. T41144Alias CYM 5442 hydrochlorideCas No. 1783987-80-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$1,070	35 days	35 days
50 mg	$4,290	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	CYM 5442 hydrochloride is a potent and selective S1P1agonistin vitro(EC50 = 1.35 nM). Activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. Induces acute lymphopenia in mice. Brain penetrant.
Targets&IC50	S1P1 receptor:1.35 nM (EC50)
Synonyms	CYM 5442 hydrochloride

Chemical Properties

Molecular Weight	445.94
Formula	C₂₃H₂₈ClN₃O₄
Cas No.	1783987-80-3
Smiles	Cl.CCOc1ccc(cc1OCC)-c1nc(no1)-c1cccc2C(CCc12)NCCO

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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