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HyT36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase Her3. HyT36 can treat cells expressing erht induced acutely.

Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-small cell lung cancer.

pan-HER-IN-1 (Compound C5) is an irreversible, orally active Pan-HER inhibitor that exhibits IC50 values of 0.38 nM for EGFR, 1.6 nM for HER4, 2.2 nM for EGFR T790M L858R, and 3.5 nM for HER2, respectively. pan-HER-IN-1 induces apoptosis and demonstrates antitumor activities.

pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that targets EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50: 8.2 nM), and L858R (IC50: 75.1 nM). pan-HER-IN-2 induces apoptosis and possesses anti-tumor effects.

Biotin HER-2 substrate peptide serves as a substrate for the tyrosine kinases HER4 and HER2 NEU, with a Km value of 60 μm in the kinase domain of HER2 NEU.

HER2 neu (654-662) GP2 acetate is derived from the human epidermal growth factor receptor 2 (HER2-Neu, 654–662). HER2 neu (654-662) GP2 acetate induces HLA-A2-restricted cytotoxic T lymphocytes reactive to various epithelial cancers.

Thermospermine is a structural isomer of spermine that plays a role in inhibiting xylem differentiation and can enhance the translation of SAC51 and SACL1 in Arabidopsis thaliana. Thermospermine is also used in studies as a plant growth regulator and for controlling wood biomass production.

Erythromycin A enol ether is a degradation product of Erythromycin A which is a macrolide antibiotic.

β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders, including those related to lupus diseases.

D-alpha-Tocopherol acetate (Vitamin E Acetate) is hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine.

4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label that exhibits significant activity against B. subtilis.

Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) induces apoptosis in A549 cells independently of cell cycle arrest, mediated by JNK and p38 MAPK signaling pathways. These pathways are activated due to oxidative DNA damage from increased ROS generation in MNQ-treated A549 cells.

DL-α-tocopherol acetate (Vitamin E acetate) is a vitamin E derivative used as a vitamin E supplement in poultry feed.

Vanillyl butyl ether (Butyl vanillyl ether) (VBE)is a capsaicin analogue,induce sensory irritation in humans,Vanillyl butyl ether is an alkoxy-substituted benzyl derivative mainly used as a flavoring agent.

Benzyl ether (Benzyl oxide) is an organic compound commonly used to protect hydroxyl groups and is mainly used as a toughening agent for nitrocellulose, a solvent for flavors, a rubber antioxidant, and a mosquito repellent. Acetovanillone-Derived benzyl ether has antimicrobial activity.

Herniarin (Ayapanin) is a natural coumarin with antitumor effect.

DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.

Artemether (CGP 56696) is an antimalarial agent used to treat acute uncomplicated malaria.

Schisantherin A (Wuweizi ester-A) is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.

Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the m

Lipopolysaccharides from Escherichia coli O111:B4 are key components of the outer membrane of Gram-negative bacteria. As a smooth-type LPS, they consist of lipid A, an R3-type core oligosaccharide, and an O-specific polysaccharide. These LPS molecules exhibit high immunogenicity, can trigger strong immune responses and gastric disorders by activating the TLR-4 receptor on immune cells, and help maintain the structural integrity of the bacterial outer membrane while protecting against bile salts and lipid-based antibiotics. They are widely used to establish inflammation-related disease models, such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS).

Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is extracted from Siam weeds and demonstrates anti-inflammatory activity via the NF-κB pathway.

Cadherin Peptide, avian Acetate is a peptide with the sequence Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2. Cadherins are a class of type-1 transmembrane proteins.

1. Naringenin trimethyl ether (5,7,4'-Trimethoxyflavanone) shows significant molluscicidal activity with a median lethal concentration (LC(5)) of 3.9 μg mL.