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Zolbetuximab MMAE (Synonyms: IMAB362 MMAE)

Catalog No. T9901A-222 Copy Product Info
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Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.

Zolbetuximab MMAE

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Catalog No. T9901A-222
Synonyms IMAB362 MMAE

Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.

Zolbetuximab MMAE
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$1,690-In Stock
5 mg$3,430-In Stock
10 mg$4,630-In Stock
25 mg$6,880-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.
In vitro
Zolbetuximab MMAE binds to ClDN18.2-positive (CLDN18.2+) cells with high affinity and induces antibody-dependent cell-mediated cytotoxicity (ADCC). [1]
In vivo
Zolbetuximab MMAE blocked the growth of CLDN18.2+ gastric and pancreatic cancer cell line xenotransplantation (CDX) models. [1]
SynonymsIMAB362 MMAE
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
MMAE
Antigen Details
Gene ID
Uniprot ID
TargetCLDN18.2
Chemical Properties
Molecular Weight146.98 kDa
Antibody Information
IsotypeHuman IgG1 kappa-vcMMAE
Storage & Solubility Information
StorageStore at low temperature | Shipping with blue ice.

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