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Lintuzumab
(Synonyms: SGN-33, SGN33, HuM-195, HuM195) Copy Product Info
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Synonyms: SGN-33, SGN33, HuM-195, HuM195
Catalog No. T9901A-065 Copy Product Info
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Lintuzumab (HuM-195) is a non-coupled humanized mouse monoclonal antibody directed against the cell-surface myelomonocyte differentiation antigen, CD33, with anti-leukemic activity that reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells.Lintuzumab has antitumor activity and induces cell death directly via CDC or ADCC. Lintuzumab has anti-tumor activity and induces cell death directly via CDC or ADCC.
Cas No. 166089-32-3
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | In Stock | In Stock | |
| 5 mg | $463 | In Stock | In Stock | |
| 10 mg | $673 | - | In Stock | |
| 25 mg | $987 | - | In Stock | |
| 50 mg | $1,390 | - | In Stock | |
| 100 mg | $1,880 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.1% (SDS-PAGE); 98.2% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Chemical Properties
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| Description | Lintuzumab (HuM-195) is a non-coupled humanized mouse monoclonal antibody directed against the cell-surface myelomonocyte differentiation antigen, CD33, with anti-leukemic activity that reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells.Lintuzumab has antitumor activity and induces cell death directly via CDC or ADCC. Lintuzumab has anti-tumor activity and induces cell death directly via CDC or ADCC. |
| Synonyms | SGN-33, SGN33, HuM-195, HuM195 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Siglec-3/CD33 Protein (His) (TMPY-03805) at 1 μg/mL (100 μL/well) can bind Lintuzumab. The EC50 is 3.91 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Siglec-3/CD33 |
| Molecular Weight | 145.23 kDa |
| Cas No. | 166089-32-3 |
| Relative Density. | no data available |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Lintuzumab chemical structure | Lintuzumab molecular weight
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