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Anti-IGF-2 Antibody (DX-2647)
(Synonyms: DX-2647) Copy Product Info
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Synonyms: DX-2647
Catalog No. T9901A-1445 Copy Product Info
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Anti-IGF-2 Antibody (DX-2647) is a potent humanized monoclonal antibody targeting human insulin-like growth factor 2 (IGF-2), acting by disrupting its interaction with receptors such as IGF-1R and IR-A. The compound is an essential tool for investigating the role of the IGF axis in tumor proliferation and placental development, aiming to reverse abnormal tumor growth by inhibiting the IGF signaling axis.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $398 | Inquiry | Inquiry | |
| 5 mg | $1,190 | Inquiry | Inquiry | |
| 10 mg | $1,890 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-IGF-2 Antibody (DX-2647) is a potent humanized monoclonal antibody targeting human insulin-like growth factor 2 (IGF-2), acting by disrupting its interaction with receptors such as IGF-1R and IR-A. The compound is an essential tool for investigating the role of the IGF axis in tumor proliferation and placental development, aiming to reverse abnormal tumor growth by inhibiting the IGF signaling axis. |
| In vitro | In human hepatocellular carcinoma cell lines, Anti-IGF-2 Antibody (DX-2647) blocked IGF-2 binding and inhibited cell proliferation and survival signaling [1]. |
| In vivo | In human HCC xenograft models, systemic administration of Anti-IGF-2 Antibody (DX-2647) significantly inhibited tumor growth [1]. |
| Synonyms | DX-2647 |
| Clone | DX-2647 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | IGF-2 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-IGF-2 Antibody (DX-2647) chemical structure | Anti-IGF-2 Antibody (DX-2647) in vivo | Anti-IGF-2 Antibody (DX-2647) in vitro
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