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Anti-IGF-2 Antibody (DX-2647)
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Catalog No. T9901A-1445
Alias DX-2647
Anti-IGF-2 Antibody (DX-2647) is a potent humanized monoclonal antibody targeting human insulin-like growth factor 2 (IGF-2), acting by disrupting its interaction with receptors such as IGF-1R and IR-A. The compound is an essential tool for investigating the role of the IGF axis in tumor proliferation and placental development, aiming to reverse abnormal tumor growth by inhibiting the IGF signaling axis.
Anti-IGF-2 Antibody (DX-2647)
Anti-IGF-2 Antibody (DX-2647)
Copy Product Info🥰Excellent
Catalog No. T9901A-1445Alias DX-2647
Anti-IGF-2 Antibody (DX-2647) is a potent humanized monoclonal antibody targeting human insulin-like growth factor 2 (IGF-2), acting by disrupting its interaction with receptors such as IGF-1R and IR-A. The compound is an essential tool for investigating the role of the IGF axis in tumor proliferation and placental development, aiming to reverse abnormal tumor growth by inhibiting the IGF signaling axis.
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| Description | Anti-IGF-2 Antibody (DX-2647) is a potent humanized monoclonal antibody targeting human insulin-like growth factor 2 (IGF-2), acting by disrupting its interaction with receptors such as IGF-1R and IR-A. The compound is an essential tool for investigating the role of the IGF axis in tumor proliferation and placental development, aiming to reverse abnormal tumor growth by inhibiting the IGF signaling axis. |
| In vitro | In human hepatocellular carcinoma cell lines, Anti-IGF-2 Antibody (DX-2647) blocked IGF-2 binding and inhibited cell proliferation and survival signaling [1]. |
| In vivo | In human HCC xenograft models, systemic administration of Anti-IGF-2 Antibody (DX-2647) significantly inhibited tumor growth [1]. |
| Synonyms | DX-2647 |
| Clone | DX-2647 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | IGF-2 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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