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TCS 1105

🥰Excellent
Catalog No. T23444Cas No. 185391-33-7
Alias N-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide

TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.

TCS 1105

TCS 1105

🥰Excellent
Purity: 99.75%
Catalog No. T23444Alias N-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamideCas No. 185391-33-7
TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$34-In Stock
10 mg$51-In Stock
25 mg$83-In Stock
50 mg$125-In Stock
100 mg$190-In Stock
200 mg$272-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.75%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.
SynonymsN-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide
Chemical Properties
Molecular Weight296.3
FormulaC17H13FN2O2
Cas No.185391-33-7
SmilesFC1=CC=C(CNC(=O)C(=O)C2=CNC3=C2C=CC=C3)C=C1
Relative Density.1.342 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (84.37 mM), Sonication is recommended.
Ethanol: < 5.93 mg/mL, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3750 mL16.8748 mL33.7496 mL168.7479 mL
5 mM0.6750 mL3.3750 mL6.7499 mL33.7496 mL
10 mM0.3375 mL1.6875 mL3.3750 mL16.8748 mL
20 mM0.1687 mL0.8437 mL1.6875 mL8.4374 mL
50 mM0.0675 mL0.3375 mL0.6750 mL3.3750 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

TCS-1105TCS1105TCS 1105
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