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Sulfidefluor-7 AM (Synonyms: SF7-AM)

Catalog No. T34741 Copy Product Info
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Sulfidefluor-7 AM (SF7-AM) is an effective and cell permeable fluorescent probe for hydrogen sulfide (h2s). Sulfidefluor-7 AM contains acetoxy-methyl ester, which is hydrolyzed intracellular to capture the probe.

Sulfidefluor-7 AM

Copy Product Info
🥰Excellent
Catalog No. T34741
Synonyms SF7-AM

Sulfidefluor-7 AM (SF7-AM) is an effective and cell permeable fluorescent probe for hydrogen sulfide (h2s). Sulfidefluor-7 AM contains acetoxy-methyl ester, which is hydrolyzed intracellular to capture the probe.

Sulfidefluor-7 AM
Cas No. 1416872-50-8
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$69335 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Sulfidefluor-7 AM (SF7-AM) is an effective and cell permeable fluorescent probe for hydrogen sulfide (h2s). Sulfidefluor-7 AM contains acetoxy-methyl ester, which is hydrolyzed intracellular to capture the probe.
Cell Research
Cellular H2S measurement
Operation steps
1. Cell staining: Culture cells in a flat-bottom 96-well plate to an appropriate state, add SF7-AM (1 μM), and incubate at 37°C for 30 minutes.
2. Wash the wells with Hanks balanced salt solution to remove residual dye and observe under an inverted wide-field fluorescence microscope.

The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands.
SynonymsSF7-AM
Chemical Properties
Molecular Weight685.55
FormulaC31H23N7O12
Cas No.1416872-50-8
Smiles[N-]=[N+]=NC1=CC=C2C(OC3=CC(N=[N+]=[N-])=CC=C3C42OC(=O)C5=CC(=CC=C54)C(=O)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)=C1
Relative Density.no data available
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12.3 mg/mL (17.94 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4587 mL7.2934 mL14.5868 mL72.9341 mL
5 mM0.2917 mL1.4587 mL2.9174 mL14.5868 mL
10 mM0.1459 mL0.7293 mL1.4587 mL7.2934 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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