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RS47 (Compound 1a) is a small molecule (Kd = 1.1 μM) that specifically targets RelB, selectively inhibiting the non-canonical NF-κB pathway by disrupting RelB binding to target DNA. It exhibits antitumour activity in vivo and in vitro and may be used in studies of colorectal cancer and B-cell lymphoma.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $41 | - | In Stock | |
| 5 mg | $97 | - | In Stock | |
| 10 mg | $137 | - | In Stock | |
| 25 mg | $233 | - | In Stock | |
| 50 mg | $392 | - | In Stock | |
| 100 mg | $568 | - | In Stock | |
| 200 mg | $792 | - | In Stock |
| Description | RS47 (Compound 1a) is a small molecule (Kd = 1.1 μM) that specifically targets RelB, selectively inhibiting the non-canonical NF-κB pathway by disrupting RelB binding to target DNA. It exhibits antitumour activity in vivo and in vitro and may be used in studies of colorectal cancer and B-cell lymphoma. |
| Synonyms | RS-47, RS 47 |
| Molecular Weight | 354.43 |
| Formula | C18H18N4O2S |
| Cas No. | 301655-16-3 |
| Smiles | OC1=CC=C(O)C(=C1)C(=NNC=2N=CN=C3SC4=C(C32)CCCC4)C |
| Color | Brown |
| Appearance | Solid |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (56.43 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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