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RS 79948 hydrochloride

Name: RS 79948 hydrochloride
Brand: TargetMol
SKU: T23266
Rating: 4.5 (1 reviews)

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Catalog No. T23266Cas No. 186002-54-0

α2-adrenoreceptor antagonist

RS 79948 hydrochloride

😃Good

Catalog No. T23266Cas No. 186002-54-0

α2-adrenoreceptor antagonist

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description	α2-adrenoreceptor antagonist
Targets&IC50	α2A-adrenoceptor (human):0.6 nM (Kd), α2C-adrenoceptor (human):0.77 nM (Kd), α2B-adrenoceptor (human):0.46 nM (Kd), α2C-adrenoceptor (rat):0.19 nM (Kd), α2A-adrenoceptor (rat):0.42 nM (Kd), α2B-adrenoceptor (rat):0.18 nM (Kd)

Chemical Properties

Molecular Weight	400.96
Formula	C₁₉H₂₉ClN₂O₃S
Cas No.	186002-54-0
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 25 mM, Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.4940 mL	12.4701 mL	24.9401 mL	124.7007 mL
5 mM	0.4988 mL	2.4940 mL	4.9880 mL	24.9401 mL
10 mM	0.2494 mL	1.2470 mL	2.4940 mL	12.4701 mL
20 mM	0.1247 mL	0.6235 mL	1.2470 mL	6.2350 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc