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RS 79948 hydrochloride

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Catalog No. T23266Cas No. 186002-54-0

α2-adrenoreceptor antagonist

RS 79948 hydrochloride

RS 79948 hydrochloride

😃Good
Catalog No. T23266Cas No. 186002-54-0
α2-adrenoreceptor antagonist
Pack SizePriceAvailabilityQuantity
10 mgTBD35 days
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Product Introduction

Bioactivity
Description
α2-adrenoreceptor antagonist
Targets&IC50
α2C-adrenoceptor (human):0.77 nM (Kd), α2B-adrenoceptor (human):0.46 nM (Kd), α2A-adrenoceptor (human):0.6 nM (Kd), α2A adrenergic receptor (rat):0.42 nM (Kd), α2b-adrenergic receptor (rat):0.18 nM (Kd), α2c-adrenergic receptor (rat):0.19 nM (Kd)
Chemical Properties
Molecular Weight400.96
FormulaC19H29ClN2O3S
Cas No.186002-54-0
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 25 mM, Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.4940 mL12.4701 mL24.9401 mL124.7007 mL
5 mM0.4988 mL2.4940 mL4.9880 mL24.9401 mL
10 mM0.2494 mL1.2470 mL2.4940 mL12.4701 mL
20 mM0.1247 mL0.6235 mL1.2470 mL6.2350 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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