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RFRP-3 (rat) acetate is an RFamide-family neuropeptide characterized by a C-terminal Arg-Phe-NH₂ motif, consisting in rats of the 12-residue sequence VPNLPQRF-NH₂; RFRP-3 (rat) acetate(420088-80-8 Free base) exhibits functional specialization compared with related peptides such as NPFF and PrRP, acting primarily as an inhibitor of reproductive signaling; its neurons are localized to the dorsomedial hypothalamus and project to GnRH neurons and the median eminence, making RFRP-3 a critical tool for studying hypothalamic regulation of fertility, neuroendocrine signaling, and peptide evolution within the RFamide family.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $691 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
| Description | RFRP-3 (rat) acetate is an RFamide-family neuropeptide characterized by a C-terminal Arg-Phe-NH₂ motif, consisting in rats of the 12-residue sequence VPNLPQRF-NH₂; RFRP-3 (rat) acetate(420088-80-8 Free base) exhibits functional specialization compared with related peptides such as NPFF and PrRP, acting primarily as an inhibitor of reproductive signaling; its neurons are localized to the dorsomedial hypothalamus and project to GnRH neurons and the median eminence, making RFRP-3 a critical tool for studying hypothalamic regulation of fertility, neuroendocrine signaling, and peptide evolution within the RFamide family. |
| Synonyms | RFRP-3 (rat) acetate(420088-80-8 Free base), Neuropeptide NPVF (rat) acetate(420088-80-8 Free base), Neuropeptide NPVF (rat) acetate |
| Molecular Weight | 2080.37 |
| Formula | C90H138N26O27S2 |
| Smiles | C[C@H](N)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(N[C@@H](CO)C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O |
| Relative Density. | no data available |
| Sequence | Ala-Asn-Met-Glu-Ala-Gly-Thr-Met-Ser-His-Phe-Pro-Ser-Leu-Pro-Gln-Arg-Phe-NH2 |
| Sequence Short | ANMEAGTMSHFPSLPQRF |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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