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Diatrizoate meglumine

Name: Diatrizoate meglumine
Brand: TargetMol
SKU: T20637
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20637Cas No. 131-49-7

Alias Sinografin, Renovist, Renografin, Renocal, Reno, Hypaque

Diatrizoate meglumine (Renocal) is the meglumine salt of diatrizoate, it is an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography.

Diatrizoate meglumine

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Purity: 99.43%

Catalog No. T20637Alias Sinografin, Renovist, Renografin, Renocal, Reno, HypaqueCas No. 131-49-7

Diatrizoate meglumine (Renocal) is the meglumine salt of diatrizoate, it is an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$31	In Stock	In Stock
1 g	$44	In Stock	In Stock
5 g	$98	-	In Stock
10 g	$148	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.43%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Diatrizoate meglumine AI Summary

Diatrizoate meglumine exhibits a range of bioactivities including enhancement of SMN2 splice variant expression. It has an EC50 value greater than 195,000.0 nM for inhibiting Heat Shock Factor 1 (HSF1). It acts as an inhibitor of Histone Lysine Methyltransferase G9a (potency 50,118.7 nM), HP1-beta Chromodomain interactions with Methylated Histone Tails (potency 79,432.8 nM), and Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1) (potency 56,234.1 nM). Additionally, it induces DNA re-replication in MCF 10a normal breast cells with a potency of 29,092.9 nM and in SW480 colon adenocarcinoma cells with a potency of 13.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Diatrizoate meglumine (Renocal) is the meglumine salt of diatrizoate, it is an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography.
Synonyms	Sinografin, Renovist, Renografin, Renocal, Reno, Hypaque

Chemical Properties

Molecular Weight	809.13
Formula	C₁₈H₂₆I₃N₃O₉
Cas No.	131-49-7
Smiles	CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)NC(=O)C)I.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
Relative Density.	1.9465 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (74.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2359 mL	6.1795 mL	12.3590 mL	61.7948 mL
5 mM	0.2472 mL	1.2359 mL	2.4718 mL	12.3590 mL
10 mM	0.1236 mL	0.6179 mL	1.2359 mL	6.1795 mL
20 mM	0.0618 mL	0.3090 mL	0.6179 mL	3.0897 mL
50 mM	0.0247 mL	0.1236 mL	0.2472 mL	1.2359 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Diatrizoate meglumine