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EGTA-AM

Name: EGTA-AM
Brand: TargetMol
SKU: T13673
Price: 75 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13673Cas No. 99590-86-0

Alias EGTA Acetoxymethyl ester

EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.

EGTA-AM

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Purity: 97.45%

Catalog No. T13673Alias EGTA Acetoxymethyl esterCas No. 99590-86-0

EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.

Pack Size	Price	Availability
1 mg	$75	In Stock
5 mg	$152	In Stock
10 mg	$245	In Stock
25 mg	$437	In Stock
50 mg	$646	In Stock
100 mg	$919	In Stock
200 mg	$1,250	In Stock

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Batch Information

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Purity:97.45%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.
In vitro	Many spontaneous but stimulus-dependent EPSCs are observed after the stimulus and are blocked by DNQX and reduced by EGTA-AM (50 μM)[1].
Synonyms	EGTA Acetoxymethyl ester

Chemical Properties

Molecular Weight	668.6
Formula	C₂₆H₄₀N₂O₁₈
Cas No.	99590-86-0
Smiles	CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O
Relative Density.	1.303 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (119.58 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4957 mL	7.4783 mL	14.9566 mL	74.7831 mL
5 mM	0.2991 mL	1.4957 mL	2.9913 mL	14.9566 mL
10 mM	0.1496 mL	0.7478 mL	1.4957 mL	7.4783 mL
20 mM	0.0748 mL	0.3739 mL	0.7478 mL	3.7392 mL
50 mM	0.0299 mL	0.1496 mL	0.2991 mL	1.4957 mL
100 mM	0.0150 mL	0.0748 mL	0.1496 mL	0.7478 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

EGTA-AMEGTAAMEGTA AM