Anti-Polyubiquitin Antibody represents a highly specialized monoclonal antibody specifically engineered to target the complex lysine-linked polyubiquitin chains such as the K48 or K63 branched structures with exceptional binding affinity and selectivity, effectively facilitating the measurable detection and quantification of polyubiquitinated substrates across various preclinical experimental models to evaluate the dynamic regulation of the ubiquitin-proteasome system during strictly monitored laboratory observation periods.