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(±)11(12)-EET-d11 Methyl ester

Catalog No. TMIT-0194 Copy Product Info
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(±)11(12)-EET-d11 Methyl ester is the deuterated form of (±)11(12)-EET methyl ester, which itself is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET). This compound does not induce β-arrestin recruitment by the G protein-coupled receptor GPR132 and also does not enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. Serving as a negative control, 11,12-EET methyl ester is used to explore the structure-function relationship of 11,12-EET, aiding in the study of the oxidized fatty acid-GPR132 signaling axis in hematopoiesis.

(±)11(12)-EET-d11 Methyl ester

Copy Product Info
🥰Excellent
Catalog No. TMIT-0194

(±)11(12)-EET-d11 Methyl ester is the deuterated form of (±)11(12)-EET methyl ester, which itself is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET). This compound does not induce β-arrestin recruitment by the G protein-coupled receptor GPR132 and also does not enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. Serving as a negative control, 11,12-EET methyl ester is used to explore the structure-function relationship of 11,12-EET, aiding in the study of the oxidized fatty acid-GPR132 signaling axis in hematopoiesis.


(±)11
(12)-EET-d11 Methyl ester
Other Forms of (±)11(12)-EET-d11 Methyl ester:
(±)11(12)-EET methyl esterT21134390693-45-1
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Product Introduction

Bioactivity
Description
(±)11(12)-EET-d11 Methyl ester is the deuterated form of (±)11(12)-EET methyl ester, which itself is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET). This compound does not induce β-arrestin recruitment by the G protein-coupled receptor GPR132 and also does not enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. Serving as a negative control, 11,12-EET methyl ester is used to explore the structure-function relationship of 11,12-EET, aiding in the study of the oxidized fatty acid-GPR132 signaling axis in hematopoiesis.
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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