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1,1-Bis(Methylthio)-2-Nitroethylene

🥰Excellent
Catalog No. T1345Cas No. 13623-94-4

1,1-Bis(Methylthio)-2-Nitroethylene (1,1-BMNE) has a variety of biochemical and physiological effects. It inhibits the activity of enzymes involved in the metabolism of drugs and other compounds, such as cytochrome P450 and acetylcholinesterase.

1,1-Bis(Methylthio)-2-Nitroethylene

1,1-Bis(Methylthio)-2-Nitroethylene

🥰Excellent
Purity: 99.19%
Catalog No. T1345Cas No. 13623-94-4
1,1-Bis(Methylthio)-2-Nitroethylene (1,1-BMNE) has a variety of biochemical and physiological effects. It inhibits the activity of enzymes involved in the metabolism of drugs and other compounds, such as cytochrome P450 and acetylcholinesterase.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.19%
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Product Introduction

Bioactivity
Description
1,1-Bis(Methylthio)-2-Nitroethylene (1,1-BMNE) has a variety of biochemical and physiological effects. It inhibits the activity of enzymes involved in the metabolism of drugs and other compounds, such as cytochrome P450 and acetylcholinesterase.
Chemical Properties
Molecular Weight165.23
FormulaC4H7NO2S2
Cas No.13623-94-4
SmilesCSC(SC)=C[N+]([O-])=O
Relative Density.1.331 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (302.61 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.0522 mL30.2608 mL60.5217 mL302.6085 mL
5 mM1.2104 mL6.0522 mL12.1043 mL60.5217 mL
10 mM0.6052 mL3.0261 mL6.0522 mL30.2608 mL
20 mM0.3026 mL1.5130 mL3.0261 mL15.1304 mL
50 mM0.1210 mL0.6052 mL1.2104 mL6.0522 mL
100 mM0.0605 mL0.3026 mL0.6052 mL3.0261 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1,1-Bis(Methylthio)-2-Nitroethylene1,1Bis(Methylthio)2Nitroethylene1,1 Bis(Methylthio) 2 Nitroethylene
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