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(S)-(-)-HA 966

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Catalog No. T23298Cas No. 111821-58-0
Alias (S)-(-)-HA-966

(S)-(-)-HA 966 is a NMDA receptor antagonist which exhibits potent anticonvulsant effects and has shown efficacy in experimental models of neurological diseases.

(S)-(-)-HA 966

(S)-(-)-HA 966

😃Good
Catalog No. T23298Alias (S)-(-)-HA-966Cas No. 111821-58-0
(S)-(-)-HA 966 is a NMDA receptor antagonist which exhibits potent anticonvulsant effects and has shown efficacy in experimental models of neurological diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$8376-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
(S)-(-)-HA 966 is a NMDA receptor antagonist which exhibits potent anticonvulsant effects and has shown efficacy in experimental models of neurological diseases.
Synonyms(S)-(-)-HA-966
Chemical Properties
Molecular Weight116.12
FormulaC4H8N2O2
Cas No.111821-58-0
SmilesO=C1[C@@H](N)CCN1O
Relative Density.1.436 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mM, Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM8.6118 mL43.0589 mL86.1178 mL430.5890 mL
5 mM1.7224 mL8.6118 mL17.2236 mL86.1178 mL
10 mM0.8612 mL4.3059 mL8.6118 mL43.0589 mL
20 mM0.4306 mL2.1529 mL4.3059 mL21.5295 mL
50 mM0.1722 mL0.8612 mL1.7224 mL8.6118 mL
100 mM0.0861 mL0.4306 mL0.8612 mL4.3059 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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