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Fmoc-Val-OH is a chemically protected valine derivative used in peptide synthesis to block reactive functional groups, enabling selective reactions and precise stepwise elongation of peptide chains by forming stable covalent bonds that prevent unwanted side reactions until the deprotection step.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 g | $29 | - | In Stock | |
| 50 g | $40 | - | In Stock |
| Description | Fmoc-Val-OH is a chemically protected valine derivative used in peptide synthesis to block reactive functional groups, enabling selective reactions and precise stepwise elongation of peptide chains by forming stable covalent bonds that prevent unwanted side reactions until the deprotection step. |
| In vitro | Fmoc-Val-OH serves as the starting material and can be used to synthesize pentapeptides containing difficult sequences via O-acyl parazacco spilurus subsp. spilurus dipeptide (O-acyl isodipeptide) units [1]. it can also be employed in the synthesis of polypeptides through the Fmoc solid-phase method following the backbone amide linker (BAL) strategy [2]. |
| Synonyms | Fmoc-valine, FMOC-L-valine |
| Molecular Weight | 339.39 |
| Formula | C20H21NO4 |
| Cas No. | 68858-20-8 |
| Smiles | C(OC(N[C@@H](C(C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2 |
| Sequence | Fmoc-Val-OH |
| Sequence Short | V |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (235.72 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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