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GE11

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Catalog No. TP3986Cas No. 875142-25-9

GE11 is an active peptide that can combine with colloidal drug delivery systems to serve as an intelligent carrier for antitumor drugs, applicable in cancer research.

GE11

GE11

😃Good
Catalog No. TP3986Cas No. 875142-25-9
GE11 is an active peptide that can combine with colloidal drug delivery systems to serve as an intelligent carrier for antitumor drugs, applicable in cancer research.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
GE11 is an active peptide that can combine with colloidal drug delivery systems to serve as an intelligent carrier for antitumor drugs, applicable in cancer research.
In vitro
GE11 is an effective EGFR ligand, known as a dodecapeptide, which binds to the epidermal growth factor receptor (EGFR) with high affinity and selective specificity. It is utilized for the diagnosis and radiotherapy of EGFR-positive tumors, as well as the targeted delivery of gene therapy and chemotherapy drugs.
Chemical Properties
Molecular Weight1540.68
FormulaC75H97N17O19
Cas No.875142-25-9
SmilesC([C@H](NC([C@H](CC1=CN=CN1)NC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)C(N[C@@H](CC3=CC=C(O)C=C3)C(NCC(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)[C@@H](C)C)=O)CC(N)=O)=O)CCC(N)=O)=O)CCC5)[C@@H](C)O)=O)=O)=O)=O)C=6C=7C(NC6)=CC=CC7
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy GE11 | purchase GE11 | GE11 cost | order GE11 | GE11 chemical structure | GE11 in vitro | GE11 formula | GE11 molecular weight
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