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Anti-Nectin-2 Antibody (1B632) is a Mouse antibody targeting Nectin-2. Anti-Nectin-2 Antibody (1B632) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-Nectin-2 Antibody (1B632) is a Mouse antibody targeting Nectin-2. Anti-Nectin-2 Antibody (1B632) can be used in ELISA. |
Alias | PVRR2, PRR2, poliovirus receptor-related 2 (herpesvirus entry mediator B), Nectin-2, HVEB, CD112 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1B632 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD112 / Nectin2 extracellular domain (rhCD112; TMPY-00747; Met1-Leu360; NP_002847.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
Conjucates | Unconjugated |
Immunogen | Human cell-derived rhCD112 (TMPY-00747) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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