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Poly-L-lysine (hydrobromide) (MW 150000-300000)
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Catalog No. TCL-02174
Poly-L-lysine hydrobromide (MW 150000-300000) is a lysine polymer that acts as a nonspecific cell attachment factor. It facilitates cell adhesion to solid substrates and can serve as a coating matrix for culture dishes and slides. Additionally, it exhibits anticancer activity against melanoma and lymphoma. Poly-L-lysine hydrobromide (MW 150000-300000) is also applicable in combination with hyperthermia, magnetic resonance imaging, and cancer cell detection.
Poly-L-lysine (hydrobromide) (MW 150000-300000)
Poly-L-lysine (hydrobromide) (MW 150000-300000)
Copy Product Info😃Good
Catalog No. TCL-02174
Poly-L-lysine hydrobromide (MW 150000-300000) is a lysine polymer that acts as a nonspecific cell attachment factor. It facilitates cell adhesion to solid substrates and can serve as a coating matrix for culture dishes and slides. Additionally, it exhibits anticancer activity against melanoma and lymphoma. Poly-L-lysine hydrobromide (MW 150000-300000) is also applicable in combination with hyperthermia, magnetic resonance imaging, and cancer cell detection.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | Poly-L-lysine hydrobromide (MW 150000-300000) is a lysine polymer that acts as a nonspecific cell attachment factor. It facilitates cell adhesion to solid substrates and can serve as a coating matrix for culture dishes and slides. Additionally, it exhibits anticancer activity against melanoma and lymphoma. Poly-L-lysine hydrobromide (MW 150000-300000) is also applicable in combination with hyperthermia, magnetic resonance imaging, and cancer cell detection. |
| In vitro | Poly-L-lysine hydrobromide (MW 150000-300000) exhibits cytotoxic effects in B16F10 and L1210 cells at concentrations ranging from 0-500 µg/mL over 67 hours, with IC50 values of 25 and 275 µg/mL, respectively. Additionally, this compound is used to design magnetic nanoparticles for combined hyperthermia, magnetic resonance imaging, and cancer cell detection. It also inhibits MHCK A phosphorylation of synthetic peptide MH-3, with an IC50 around 0.5 µg/mL. |
| In vivo | Poly-L-lysine hydrobromide (MW 150000-300000) is used for synthesizing nanoclusters (i.v.) to enable negative contrast imaging of endometriotic lesions in mice via positron emission tomography. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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