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Poly-L-lysine (hydrobromide) (MW 150000-300000)
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Catalog No. TCL-02174
Poly-L-lysine hydrobromide (MW 150000-300000) is a lysine polymer that acts as a nonspecific cell attachment factor. It facilitates cell adhesion to solid substrates and can serve as a coating matrix for culture dishes and slides. Additionally, it exhibits anticancer activity against melanoma and lymphoma. Poly-L-lysine hydrobromide (MW 150000-300000) is also applicable in combination with hyperthermia, magnetic resonance imaging, and cancer cell detection.
Poly-L-lysine (hydrobromide) (MW 150000-300000)
Poly-L-lysine (hydrobromide) (MW 150000-300000)
😃Good
Catalog No. TCL-02174
Poly-L-lysine hydrobromide (MW 150000-300000) is a lysine polymer that acts as a nonspecific cell attachment factor. It facilitates cell adhesion to solid substrates and can serve as a coating matrix for culture dishes and slides. Additionally, it exhibits anticancer activity against melanoma and lymphoma. Poly-L-lysine hydrobromide (MW 150000-300000) is also applicable in combination with hyperthermia, magnetic resonance imaging, and cancer cell detection.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Chemical Properties
Storage & Solubility Information
| Description | Poly-L-lysine hydrobromide (MW 150000-300000) is a lysine polymer that acts as a nonspecific cell attachment factor. It facilitates cell adhesion to solid substrates and can serve as a coating matrix for culture dishes and slides. Additionally, it exhibits anticancer activity against melanoma and lymphoma. Poly-L-lysine hydrobromide (MW 150000-300000) is also applicable in combination with hyperthermia, magnetic resonance imaging, and cancer cell detection. |
| In vitro | Poly-L-lysine hydrobromide (MW 150000-300000) exhibits cytotoxic effects in B16F10 and L1210 cells at concentrations ranging from 0-500 µg/mL over 67 hours, with IC50 values of 25 and 275 µg/mL, respectively. Additionally, this compound is used to design magnetic nanoparticles for combined hyperthermia, magnetic resonance imaging, and cancer cell detection. It also inhibits MHCK A phosphorylation of synthetic peptide MH-3, with an IC50 around 0.5 µg/mL. |
| In vivo | Poly-L-lysine hydrobromide (MW 150000-300000) is used for synthesizing nanoclusters (i.v.) to enable negative contrast imaging of endometriotic lesions in mice via positron emission tomography. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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