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(S)-GNE-140

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Catalog No. T13450Cas No. 2003234-64-6

(S)-GNE-140 is the less active enantiomer of GNE-140.

(S)-GNE-140
Other Forms of (S)-GNE-140:

(S)-GNE-140

🥰Excellent
Catalog No. T13450Cas No. 2003234-64-6
(S)-GNE-140 is the less active enantiomer of GNE-140.
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Product Introduction

Bioactivity
Description
(S)-GNE-140 is the less active enantiomer of GNE-140.
Chemical Properties
Molecular Weight499.05
FormulaC25H23ClN2O3S2
Cas No.2003234-64-6
SmilesOC1=C(Sc2ccccc2Cl)C(=O)N[C@](C1)(c1ccsc1)c1ccc(cc1)N1CCOCC1
Relative Density.1.46 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 14 mg/mL (28.05 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0038 mL10.0190 mL20.0381 mL100.1904 mL
5 mM0.4008 mL2.0038 mL4.0076 mL20.0381 mL
10 mM0.2004 mL1.0019 mL2.0038 mL10.0190 mL
20 mM0.1002 mL0.5010 mL1.0019 mL5.0095 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LDHAGNE-140GNE140GNE 140(S)GNE140(S) GNE 140
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