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N-Acetylcarnosine acetate

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Catalog No. TP1088L
Alias N-Acetyl-L-carnosine acetate, N-Acetyl carnosine acetate

N-Acetylcarnosine acetate (N-Acetyl-L-carnosine acetate), a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic drug in human cataracts

N-Acetylcarnosine acetate
Other Forms of N-Acetylcarnosine acetate:
N-AcetylcarnosineTP108856353-15-2
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N-Acetylcarnosine acetate

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Catalog No. TP1088LAlias N-Acetyl-L-carnosine acetate, N-Acetyl carnosine acetate
N-Acetylcarnosine acetate (N-Acetyl-L-carnosine acetate), a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic drug in human cataracts
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100 mg$55InquiryInquiry
200 mg$82InquiryInquiry
500 mg$155InquiryInquiry
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Product Introduction

Bioactivity
Description
N-Acetylcarnosine acetate (N-Acetyl-L-carnosine acetate), a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic drug in human cataracts
In vitro
Right eyes of the rabbits (male grey chinchilla rabbits aged 3-4 months weighing 2-3 k) are instilled with 80 μL of formulation A containing 1 % N-Acetylcarnosine acetate. The N-Acetylcarnosine acetate prodrug eye drops optimize the clinical effects for the treatment of ophthalmic disorders (such as prevention and reversal of cataracts in human and animal eyes)[1].
SynonymsN-Acetyl-L-carnosine acetate, N-Acetyl carnosine acetate
Chemical Properties
Molecular Weight328.32
FormulaC13H20N4O6
SmilesCC(NCCC(N[C@@H](CC1=CN=CN1)C(O)=O)=O)=O.CC(O)=O
SequenceAc-bAla-His-OH
Sequence ShortXH
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-Acetyl-L-carnosine AcetateN-Acetylcarnosine AcetateN-Acetyl carnosine Acetate
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