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Anti-VE-Cadherin Antibody (3L899) (Synonyms: cadherin 5, type 2 (vascular endothelium))
Catalog No. TMAY-03800 Copy Product Info
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Anti-VE-Cadherin Antibody (3L899) is a Mouse antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (3L899) can be used in WB.
Anti-VE-Cadherin Antibody (3L899)
Copy Product Info🥰Excellent
Catalog No. TMAY-03800
Synonyms cadherin 5, type 2 (vascular endothelium)
Anti-VE-Cadherin Antibody (3L899) is a Mouse antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (3L899) can be used in WB.
Anti-VE-Cadherin Antibody
(3L899)
(3L899)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-VE-Cadherin Antibody (3L899) is a Mouse antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (3L899) can be used in WB. |
| Synonyms | cadherin 5, type 2 (vascular endothelium) |
| Ig Type | Mouse IgG2a |
| Clone | 3L899 |
| Reactivity | Rat |
| Specificity | Rat VE-Cadherin |
| Verified Activity | Anti-CDH5 mouse monoclonal antibody at 1:500 dilution. -Lane A: A549 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:88 kDa. -Observed band size:78 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat VE-Cadherin / CD144 / CDH5 (rR VE-Cadherin / CD144 / CDH5; TMPY-03305; NP_001100877.1; Met1-Gln585). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat VE-Cadherin / CD144 / CDH5 protein (TMPY-03305) |
| Antigen Species | Rat |
| Biology Area | Hemangioblast Markers, Cardiac Stem Cell Markers |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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