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3-O-Caffeoylshikimic acid (Compound 8) is a phenolic compound isolated from Livistona chinensis that exhibits antioxidant activity and inhibits the proliferation of multiple human cancer cell lines, including HepG2, HL-60, K562, and CNE-1, with IC50 values ranging from 5 to 150 μM, supporting its relevance in anticancer and oxidative stress research.

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| Description | 3-O-Caffeoylshikimic acid (Compound 8) is a phenolic compound isolated from Livistona chinensis that exhibits antioxidant activity and inhibits the proliferation of multiple human cancer cell lines, including HepG2, HL-60, K562, and CNE-1, with IC50 values ranging from 5 to 150 μM, supporting its relevance in anticancer and oxidative stress research. |
| In vitro | Method: Phenolic compounds isolated from Livistona chinensis fruits were tested for antioxidant activity and antiproliferative effects against HepG2, HL-60, K562, and CNE-1 cancer cell lines. Result: Several compounds exhibited potent antioxidant activity and antiproliferative effects with IC50 values ranging from 5 to 150 μM across multiple human cancer cell lines[1]. |
| Molecular Weight | 336.3 |
| Formula | C16H16O8 |
| Cas No. | 180981-12-8 |
| Smiles | O(C(/C=C/C1=CC(O)=C(O)C=C1)=O)[C@@H]2C=C(C(O)=O)C[C@@H](O)[C@@H]2O |
| Color | White |
| Appearance | Solid |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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