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Ebronucimab (Synonyms: AK102, AK 102)

Catalog No. T80608 Copy Product Info
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Ebronucimab (AK102) is an IgG1 antibody targeting PCSK9 that lowers LDL-C, TC, Non-HDL-C, and ApoB, and raises, HDL-C and Apo A-I for the treatment of primary hypercholesterolemia and mixed hyperlipidemia and heterozygous familial hypercholesterolemia (HeFH).

Ebronucimab

Copy Product Info
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Catalog No. T80608
Synonyms AK102, AK 102

Ebronucimab (AK102) is an IgG1 antibody targeting PCSK9 that lowers LDL-C, TC, Non-HDL-C, and ApoB, and raises, HDL-C and Apo A-I for the treatment of primary hypercholesterolemia and mixed hyperlipidemia and heterozygous familial hypercholesterolemia (HeFH).

Ebronucimab
Cas No. 2304800-90-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$232-In Stock
5 mg$578-In Stock
10 mg$828-In Stock
25 mg$1,260-In Stock
50 mg$1,680-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95.0% (SDS-PAGE); 95.65% (SEC-HPLC)
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Description
Ebronucimab (AK102) is an IgG1 antibody targeting PCSK9 that lowers LDL-C, TC, Non-HDL-C, and ApoB, and raises, HDL-C and Apo A-I for the treatment of primary hypercholesterolemia and mixed hyperlipidemia and heterozygous familial hypercholesterolemia (HeFH).
In vivo
In a multi-center randomized controlled trial conducted among Chinese patients with hypercholesterolemia, Ebronucimab, administered at 450 mg every 4 weeks or 150 mg every 2 weeks, significantly reduced serum LDL-C levels over 12 weeks (by approximately 59.13% and 60.43%, respectively), and showed high LDL-C goal achievement rates across different cardiovascular risk categories[1].
SynonymsAK102, AK 102
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetPCSK9
Chemical Properties
Molecular Weight144.76 kDa
Cas No.2304800-90-4
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature | Shipping with blue ice/Shipping at ambient temperature.

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