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Oxyfluorfen

Name: Oxyfluorfen
Brand: TargetMol
SKU: T20663
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20663Cas No. 42874-03-3

Alias RH-2915, RH 2915, Koltar, Goldate, Galigan, Boxer

Oxyfluorfen (Boxer), a herbicide of the nitrodiphenyl ether class, is used to control annual and perennial broad-leaved weeds and sedges in a variety of field crops.

Oxyfluorfen

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Purity: 99.28%

Catalog No. T20663Alias RH-2915, RH 2915, Koltar, Goldate, Galigan, BoxerCas No. 42874-03-3

Oxyfluorfen (Boxer), a herbicide of the nitrodiphenyl ether class, is used to control annual and perennial broad-leaved weeds and sedges in a variety of field crops.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$30	In Stock	In Stock
50 mg	$41	In Stock	In Stock
100 mg	$57	-	In Stock
500 mg	$173	-	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.28%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Oxyfluorfen AI Summary

Oxyfluorfen exhibits a broad spectrum of bioactivities, functioning both as an antagonist and an activator in multiple signaling pathways. It acts as an antagonist to thyroid hormone receptor beta, farnesoid X receptor, androgen receptor, peroxisome proliferator-activated receptor gamma (PPARγ), and peroxisome proliferator-activated receptor delta (PPARδ). Alternatively, it activates the nuclear factor-kappa B (NF-kB) signaling pathway, rat pregnane X receptor (rPXR) signaling pathway, peroxisome proliferator-activated receptor alpha (PPARα) signaling pathway, and human pregnane X receptor (PXR) signaling pathway. As an herbicidal agent, Oxyfluorfen shows significant activity against various weeds, including Prosopis farcta, glyphosate-resistant Conyza canadensis (horseweed), Cyperus rotundus, Malva sylvestris, and Chenopodium murale, achieving high control levels in field assays. It also possesses strong phytotoxic properties against Scenedesmus acutus and Zea mays, impacting parameters such as chlorophyll content, carotenoid biosynthesis, protoporphyrinogen IX oxidase, and ethane production. The compound exerts growth inhibition in Scenedesmus acutus and Echinochloa esculenta, with IC50 values for various assays ranging from 7.079 nM to 100.0 nM. Moreover, it has a pKa value of 7.63, indicative of its acidity, and a log P value of 4.7, suggesting a relatively high lipophilicity which is critical for its absorption and distribution in biological systems. Additionally, Oxyfluorfen has demonstrated protective activities against oxyfluorfen-induced phytotoxicity in Scenedesmus acutus, reducing protoporphyrin-9 accumulation, decreasing ethane formation, and enhancing chlorophyll content and cell density under specific conditions. This comprehensive profile reveals the versatility of Oxyfluorfen in various bioactive roles and its potential applications in both agricultural and medicinal fields..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Oxyfluorfen (Boxer), a herbicide of the nitrodiphenyl ether class, is used to control annual and perennial broad-leaved weeds and sedges in a variety of field crops.
Synonyms	RH-2915, RH 2915, Koltar, Goldate, Galigan, Boxer

Chemical Properties

Molecular Weight	361.7
Formula	C₁₅H₁₁ClF₃NO₄
Cas No.	42874-03-3
Smiles	CCOc1cc(Oc2ccc(cc2Cl)C(F)(F)F)ccc1[N+]([O-])=O
Relative Density.	1.402 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 123.75 mg/mL (342.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (9.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7647 mL	13.8236 mL	27.6472 mL	138.2361 mL
5 mM	0.5529 mL	2.7647 mL	5.5294 mL	27.6472 mL
10 mM	0.2765 mL	1.3824 mL	2.7647 mL	13.8236 mL
20 mM	0.1382 mL	0.6912 mL	1.3824 mL	6.9118 mL
50 mM	0.0553 mL	0.2765 mL	0.5529 mL	2.7647 mL
100 mM	0.0276 mL	0.1382 mL	0.2765 mL	1.3824 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc