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(R)-(+)-HA-966

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Catalog No. T12637Cas No. 123931-04-4
Alias (+)-HA-966

(R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine, has the potential for neuropathic and acute pain.

(R)-(+)-HA-966

(R)-(+)-HA-966

😃Good
Catalog No. T12637Alias (+)-HA-966Cas No. 123931-04-4
(R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine, has the potential for neuropathic and acute pain.
Pack SizePriceAvailabilityQuantity
5 mg$9706-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Product Introduction

Bioactivity
Description
(R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine, has the potential for neuropathic and acute pain.
In vivo
(+)-HA-966 (30, 100 mg/kg; IP) dose-dependently blocks the enhancement of dopamine synthesis induced in the nucleus accumbens by amphetamine, but is without effect on the increase in dopamine synthesis in the striatum in male BKTO mice (20-30g)[1]. (R)-(+)-HA-966 significantly attenuates the dose-dependent pressor response and the associated tachycardic response elicited by systemic NMDA (125, 250, 500, and 1000 mg/kg; i.v.)[3].
Synonyms(+)-HA-966
Chemical Properties
Molecular Weight116.12
FormulaC4H8N2O2
Cas No.123931-04-4
Relative Density.1.436g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

glycine site of the NMDA receptor(R)(+)HA966(R) (+) HA 966
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