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Thalidomide-NH-CH2-COOH TFA

Name: Thalidomide-NH-CH2-COOH TFA
Brand: TargetMol
SKU: T50060
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T50060Cas No. 2377032-39-6

2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.

Thalidomide-NH-CH2-COOH TFA

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Purity: 95.00%

Catalog No. T50060Cas No. 2377032-39-6

2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$31	In Stock	In Stock
5 mg	$72	In Stock	In Stock
10 mg	$107	In Stock	In Stock
25 mg	$183	In Stock	In Stock
50 mg	$272	In Stock	In Stock
100 mg	$386	In Stock	In Stock
200 mg	$527	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$83	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:95.00%

Appearance:solid

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.

Chemical Properties

Molecular Weight	445.3036
Formula	C₁₇H₁₄F₃N₃O₈
Cas No.	2377032-39-6
Smiles	OC(=O)C(F)(F)F.OC(=O)CNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (112.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2457 mL	11.2283 mL	22.4566 mL	112.2829 mL
5 mM	0.4491 mL	2.2457 mL	4.4913 mL	22.4566 mL
10 mM	0.2246 mL	1.1228 mL	2.2457 mL	11.2283 mL
20 mM	0.1123 mL	0.5614 mL	1.1228 mL	5.6141 mL
50 mM	0.0449 mL	0.2246 mL	0.4491 mL	2.2457 mL
100 mM	0.0225 mL	0.1123 mL	0.2246 mL	1.1228 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc