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3,3'-Dihexyloxacarbocyanine iodide

Name: 3,3'-Dihexyloxacarbocyanine iodide
Brand: TargetMol
SKU: T18884
Rating: 4.5 (1 reviews)

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Catalog No. T18884Cas No. 53213-82-4

Alias DiOC6(3) iodide

3,3'-Dihexyloxacarbocyanine iodide (DiOC6(3)) is a carbocyanine dye used to monitor changes in mitochondrial membrane potential.

3,3'-Dihexyloxacarbocyanine iodide

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Catalog No. T18884Alias DiOC6(3) iodideCas No. 53213-82-4

3,3'-Dihexyloxacarbocyanine iodide (DiOC6(3)) is a carbocyanine dye used to monitor changes in mitochondrial membrane potential.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$383	35 days	35 days
1 g	$717	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	3,3'-Dihexyloxacarbocyanine iodide (DiOC6(3)) is a carbocyanine dye used to monitor changes in mitochondrial membrane potential.
In vitro	The addition of cells to the cuvette containing 0.25 μM 3,3'-Dihexyloxacarbocyanine iodide (DiOCg(3)) leads to an increase in fluorescence, equilibration is rapid and is complete by 4 min. When f-met-leu-phe (10-7 M) is added to neutrophils preequilibrated with DiOCg(3), there is a short lag period of 5 seconds. The lag period is followed by a rapid loss of fluorescence. Examination of DiOCg(3) loaded neutrophils using fluorescence microscopy demonstrates that in resting neutrophils the brightest fluorescence is associated with long thin organelles that correspond to the distribution of mitochondria.
Synonyms	DiOC6(3) iodide

Chemical Properties

Molecular Weight	572.52
Formula	C₂₉H₃₇IN₂O₂
Cas No.	53213-82-4
Smiles	[I-].CCCCCCN1\C(Oc2ccccc12)=C\C=C\c1oc2ccccc2[n+]1CCCCCC
Relative Density.	1.2837 g/cm3 (Estimated)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 62.5 mg/mL (109.17 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 2.5 mg/mL (4.37 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7467 mL	8.7333 mL	17.4666 mL	87.3332 mL
5 mM	0.3493 mL	1.7467 mL	3.4933 mL	17.4666 mL
10 mM	0.1747 mL	0.8733 mL	1.7467 mL	8.7333 mL
20 mM	0.0873 mL	0.4367 mL	0.8733 mL	4.3667 mL
50 mM	0.0349 mL	0.1747 mL	0.3493 mL	1.7467 mL
100 mM	0.0175 mL	0.0873 mL	0.1747 mL	0.8733 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DiOC6(3) Iodide3,3'-Dihexyloxacarbocyanine Iodide3,3'Dihexyloxacarbocyanine iodide3,3' Dihexyloxacarbocyanine iodide

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