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Atigotatug
(Synonyms: BMS-986012, BMS986012) Copy Product Info
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Synonyms: BMS-986012, BMS986012
Catalog No. T77451 Copy Product Info
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Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.31% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research. |
| In vitro | Atigotatug binds to SCLC cell line specific and dose-dependent with EC50 ranges of 6 to 132 nmol/L, respectively. Atigotatug specifically binds FucGM1 with high affinity and acts as an IgG1 mAb, avoiding the need for T cell-dependent class switching. [1] |
| In vivo | Atigotatug (0.01 to 3 mg/kg) showed antitumor activity in human SCLC tumor xenotransplantation and PDX models. [1] |
| Synonyms | BMS-986012, BMS986012 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | GM1 |
| Molecular Weight | 145.9 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Atigotatug chemical structure | Atigotatug in vivo | Atigotatug in vitro | Atigotatug molecular weight
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