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Atigotatug
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Catalog No. T77451
Alias BMS-986012, BMS986012
Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research.
Atigotatug
Atigotatug
Copy Product Info😃Good
Catalog No. T77451Alias BMS-986012, BMS986012
Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.31% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research. |
| In vitro | Atigotatug binds to SCLC cell line specific and dose-dependent with EC50 ranges of 6 to 132 nmol/L, respectively. Atigotatug specifically binds FucGM1 with high affinity and acts as an IgG1 mAb, avoiding the need for T cell-dependent class switching. [1] |
| In vivo | Atigotatug (0.01 to 3 mg/kg) showed antitumor activity in human SCLC tumor xenotransplantation and PDX models. [1] |
| Synonyms | BMS-986012, BMS986012 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | GM1 |
| Molecular Weight | 145.9 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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