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Atigotatug
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Catalog No. T77451
Alias BMS-986012, BMS986012
Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research.
Atigotatug
Atigotatug
😃Good
Catalog No. T77451Alias BMS-986012, BMS986012
Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.31% (SEC-HPLC)
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| Description | Atigotatug (BMS-986012) is a humanized antibody targeting fucosylated GM1 ganglioside, used in lung cancer research. |
| In vitro | Atigotatug binds to SCLC cell line specific and dose-dependent with EC50 ranges of 6 to 132 nmol/L, respectively. Atigotatug specifically binds FucGM1 with high affinity and acts as an IgG1 mAb, avoiding the need for T cell-dependent class switching. [1] |
| In vivo | Atigotatug (0.01 to 3 mg/kg) showed antitumor activity in human SCLC tumor xenotransplantation and PDX models. [1] |
| Synonyms | BMS-986012, BMS986012 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | GM1 |
| Molecular Weight | 145.9 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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