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15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
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Catalog No. T211569Cas No. 1947405-90-4
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 µM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM.
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
😃Good
Catalog No. T211569Cas No. 1947405-90-4
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 µM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | 15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 µM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM. |
| Targets&IC50 | PPARγ:2 μM (EC50) |
| Molecular Weight | 390.51 |
| Formula | C23H34O5 |
| Cas No. | 1947405-90-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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